The study was conducted to determine "The Influence of Brand Image, Product Quality and Lifestyle on Nike Shoes Purchase Decisions". This type of research is quantitative with a descriptive approach method. The population in this study are all consumers who know and have used Nike brand shoes in the city of Purwokerto with a vulnerable age of 15-45 years. The sampling technique was non-probability sampling by distributing questionnaires to 100 samples. The results showed that: 1) brand image, product quality and lifestyle together influence the purchasing decision of Nike shoes, 2) brand image has a significant effect on purchasing decisions, 3) product quality has a significant effect on purchasing decisions, 4) lifestyle does not significant effect on purchasing decisions. Based on the calculation of the coefficient of determination where the Adjusted R Square value is 0.524 or 52.4%, shoe purchasing decisions are influenced by the dependent variable (brand image, product quality and lifestyle). The remaining 47.6% is influenced by other factors not explained in this study.