This study aims to examine the influence of lifestyle, perceptions, and attitudes of consumers towards the purchase decisions of Aloe Vera Gel Nature Republic Products. The independen variables in this study were lifestyle, perceptions, and attitudes of consumer, while dependent variable was purchase decision. Population in this study were consumers who bought and used Aloe Vera Gel Nature Republic in the regency of Banyumas. Sampling in this study was used purposive sampling method, so obtained 120 observation samples. Data analysis method used to multiple regression analysis method. The analysis result of hypothesis testing indicate that lifestyle, perceptions and attitudes of consumers have a significant effect on purchase decisions. From the results of the analysis there were Consumer Attitudes that have a significant effect on Purchasing Decisions. Perception has a significant effect on purchasing decisions. Lifestyle has a significant effect on Purchasing Decisions. While the variability of all variables has an influence on purchas decisions of 76.2%