This study aims to examine and analyze the influence of corporate social responsibility, working capital turnover, managerial ownership, institutional ownership of corporate profitability as measured by ROA on the company LQ45 index. The analysis technique used is Multiple Linear Analysis. The results of this study indicate that corporate social responsibility and working capital turnover has no effect on profitability. Managerial ownership variable has a negative and significant effect on profitability. The institutional ownership variable has negatively significant effect on profitability. But simultaneously corporate social responsibility, working capital turnover, managerial ownership, institutional ownership of profitability