Background: The prevalence and severity of OA are different between the
age range of adult and old range. One of treatments using NSAIDs, NSAIDs
can cause ulcer on the upper digestive. One of the sign and symptoms is
abdominal pain occurs. The indication of side effects of these drugs in daily
life has not yet been identified. Therefore, this research was done to know
the relationship between the user of NSAIDs with abdominal pain as
manifestations of peptic ulcers.
Objective: The research aims to know the relationship abdominal pain level
events on the user of single NSAIDs compared to NSAIDs combination and
compare single NSAIDs or NSAIDs combination which could lead to the
risk of the occurrence of abdominal pain as manifestations of peptio ulcers.
Methods: This type of research is observational analytic with Cohort design
and methods of data retrieval in a retrospective of OA patients medical
record at RSUD Prof. Dr Margono Soekardjo Purwokerto.
Results: The result of correlation test of Chi Squere with the acquition
value p 0,404. P > 0,05 it’s means there is not a connection between
occurrence of abdominal pain on the ideas both of single NSAIDs and
NSAIDs combination. The value of RR 0,786 with IK 95% 0,300-2,062.
This means that patients of single NSAIDs has the possibility 0,786 times to
experience abdominal pain compared the use of NSAIDs combination. The
symptoms such as abdominal pain on the left side on the single NSAIDs
33,3 % and NSAIDs combination 50,0 % experienced nausea and vomiting
on the single NSAIDs as much as 31,7% and NSAIDs combination 58,3 %,
woke up at night because of pain in your solar plexus on single NSAIDs
35,0% and NSAIDs combination 48,3%. All three of these symptoms on
NSAIDs combination have a large percentage. This is shown that NSAIDs
combination that have the risk of occurrence of abdominal pain more
quickly as manifestations of peptic ulcers.
Conclusion: Abdominal pain level that occurs in the use single NSAIDs but
viewed from symptoms abdominal pain, NSAIDs combination which has
the risk of occurs more quickly as manifestation of peptic ulcers.