The high public interest in herbal medicine products is often
misused by traders in competing for sales of traditional medicinal products,
deviations from the manufacturing procedure, namely by adding medicinal
chemicals. The use of analytical methods simultaneously or simultaneously can be
useful to find out various possibilities, which occur in the case of adding
medicinal chemicals to traditional medicinal preparations, especially herbal
medicine. Methods: Qualitative analysis of TLC (Thin Layer Chromatography)
of reference herbs using antalgine and dexamethasone as standard. Qualitative and
quantitative analysis of reference herbs, standard antalgine, standard
dexamethasone, series of reference standard concentrations in reference herbs, and
samples analyzed using an FTIR-Chemometric spectrophotometer combined with
PCA (Pricipal Component Analysis) and PLS (Partial Least Square). Results:
The qualitative analysis method of TLC (Thin Layer Chromatography) yielded a
spot value or Rf (Retention factor) that was not the same as the standard for
comparison. Qualitative analysis methods produce different spectrum profiles of
the reference herbs (1396,46cm-1; 1419,61cm-1; 1458,18cm-1; 1519,91cm-1;
1697,36cm-1; dan 1774,51cm-1), standard antalgin (1319,31 cm-1; 1651,07cm-1;
dan 1681,93cm-1), standard dexamethasone (617,23cm-1; 1450,47cm-1; dan
1743,65cm-1) and qualitative analysis methods can determine measured levels of
reference standards in herbal medicine references. Conclusion: The FTIRChemometric
spectrophotometer analysis method which is carried out
simultaneously can be used to identify medicinal chemicals in traditional
medicinal products, especially herbs.