This study aims to analyze the influence of Non-Performing Loans (NPL), Net Interest Margin (NIM), Loan to Deposit Ratio (LDR), Operational Efficiency Ratio (OER), and Capital Adequacy Ratio (CAR) on Return On Assets (ROA) . The population in this study were all National Foreign Exchange Private Banks listed on the Indonesia Stock Exchange in 2013-2018, namely 19 banks. The sample selection uses a purposive sampling method. Based on the criteria, there are 17 banks that will be used as research samples. Data analysis was performed using, namely multiple linear regression analysis. The results of this study indicate that NIM has a significant positive effect on ROA, and NPL, LDR, and OER has a significant negative effect on ROA. While CAR have no significant negative effect on ROA.