This study aimed to examine the effect of trust, easiness, information quality, the brand image on the purchase decision. The population in this research were 45.782 students in college in Purwokerto. The sampling technique used in this study was the purposive sampling technique that generated 120 respondents. The data analysis techniques used in this study were instruments test, descriptive statistics, classical assumption tests, multiple linear regression analysis, and hypothesis testing. Based on the partial test, the results showed that Trust, Easiness, Information Quality, Brand Image have a positive and significant effect on the Purchase Decision of e-commerce lazada. While based on the simultaneous test, the results showed that Trust, Easiness, Information Quality, Brand Image simultaneously affect the purchase decision of e-commerce Lazada.