One source of antioxidants is derived from plants. Tembelekan leaf (Lantana camara) is a plant that comes from the verbenaceae family which has the potential to be a natural antioxidant. The purpose of this study was to determine the phenolic levels and antioxidant activity of the Tembelekan leaves. Methods: The method used in answering the problem formulation in this research is literature study using the seach engine Annual Reviews, PubMed, SpringerLink and Google Scholar. Results: Phenolic and antioxidant levels in each plant and the method of extraction can vary. Extracts obtained from different extraction methods are thought to show different total phenolic content, the largest phenolic content is thought to be obtained from the soxhletation method and different extraction methods are thought to show strong antioxidants, where antioxidant activity is thought to be obtained from the percolation extraction method.. Conclusion: extraction method affects total phenolic levels and antioxidant activity.