PREDIKSI AKTIVITAS ANTIKANKER OLEORESIN LADA PUTIH (Piper nigrum L.) HASIL FERMENTASI RAGI TEMPE TERHADAP SEL KANKER KOLON WiDr

JANNAH, AZIZAH ZANDRA NURUL (2020) PREDIKSI AKTIVITAS ANTIKANKER OLEORESIN LADA PUTIH (Piper nigrum L.) HASIL FERMENTASI RAGI TEMPE TERHADAP SEL KANKER KOLON WiDr. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

colon cancer is recorded as the third rank in the incidence of cancer and the second rank in the case of death in the world. Pepper oleoresin is a compound that has been scientifically proven to have anticancer activity as an alternative to modern medicine. Oleoresin can be obtained by extracting white pepper which has gone through a fermentation process using a tempeh yeast starter. Method: this research uses a Literature Review, which is a systematic, explicit, and reproducible method to identify, evaluate and synthesize research works and ideas that have been produced by researchers and practitioners. Results: white pepper fermented by tempeh yeast is predicted to have higher yield of essential oil and piperine. Oleoresin extraction using soxhlet extraction with ethanol solvent, material size 40 mesh, extraction temperature 600C-800C, and extraction time 3-4 hours are predicted to produce high yields, do not cause the essential oil evaporates and oxidize and do not cause a reduction in the identified oleoresin constituents. White pepper oleoresin fermented by tempeh yeast is predicted to have anticancer activity against colon cancer cells WiDr. Conclusion: white pepper oleoresin fermented by tempeh yeast is predicted to have anticancer activity against colon cancer cells WiDr.

Item Type: Thesis (Bachelor)
Uncontrolled Keywords: white pepper oleoresin, Piper nigrum L., tempeh yeast fermentation, Rhizopus oryzae, anticancer, colon cancer, WiDr
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Agus Imam
Date Deposited: 18 Jul 2022 05:59
Last Modified: 18 Jul 2022 05:59
URI: https://repository.ump.ac.id:80/id/eprint/12618

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