UJI AKTIVITAS ANTI KANKER KOMBINASI SUPLEMEN HERBAL HABBATUSSAUDA (Nigella sativa, L.) DENGAN 5-FLUOROURACIL TERHADAP SEL KANKER PAYUDARA T47D

AMALIA, MAYA (2019) UJI AKTIVITAS ANTI KANKER KOMBINASI SUPLEMEN HERBAL HABBATUSSAUDA (Nigella sativa, L.) DENGAN 5-FLUOROURACIL TERHADAP SEL KANKER PAYUDARA T47D. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

[img]
Preview
Text
MAYA AMALIA_JUDUL.pdf

Download (2MB) | Preview
[img]
Preview
Text
MAYA AMALIA_BAB I.pdf

Download (1MB) | Preview
[img]
Preview
Text
MAYA AMALIA_BAB II.pdf

Download (1MB) | Preview
[img] Text
MAYA AMALIA_BAB III.pdf
Restricted to Repository staff only

Download (1MB)
[img] Text
MAYA AMALIA_BAB IV.pdf
Restricted to Repository staff only

Download (1MB)
[img] Text
MAYA AMALIA_BAB V.pdf
Restricted to Repository staff only

Download (1MB)
[img]
Preview
Text
MAYA AMALIA_DAFTAR PUSTAKA.pdf

Download (1MB) | Preview
[img] Text
MAYA AMALIA_LAMPIRAN.pdf
Restricted to Repository staff only

Download (2MB)

Abstract

The high incidence rate of cancer and the unpleasant side effects of chemotherapeutic agents are the common problems that often appears. This research aimed to find out the anticancer activity from the combination of habbatussauda herbal supplement (SHH) and 5-fluorouracil (5FU) against T47D cell. The cytotoxic test method used in this research was MTT Assay with 24- hours incubation at 37oC and 5% of CO2. SHH has moderate cytotoxic activity (IC50 234,32 μg/ml). The combination of SHH with 5FU has the best synergetic effect on the concentration of 40 μg/ml SHH + 30 μg/ml 5FU with CI value is 0,5. The proliferation test was done by doubling time method. The combination of SHH and 5FU showed the effect of inhibition against the proliferation of T47D cell. However, it did not show any significant difference comparing to singular 5FU. The anticancer activity from the combination of SHH and 5FU was by inhibiting cell proliferation.

Item Type: Thesis (Bachelor)
Uncontrolled Keywords: Supplement, Habbatussauda, 5FU, T47D, cancer
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Iin Hayuningtyas
Date Deposited: 14 Mar 2022 01:21
Last Modified: 16 Mar 2022 00:58
URI: https://repository.ump.ac.id:80/id/eprint/10939

Actions (login required)

View Item View Item