PENGARUH KONDISI PENYIMPANAN TERHADAP STABILITAS KADAR FUROSEMID DI PUSKESMAS WILAYAH PURWOKERTO

INDRIANI, ADE SARI (2015) PENGARUH KONDISI PENYIMPANAN TERHADAP STABILITAS KADAR FUROSEMID DI PUSKESMAS WILAYAH PURWOKERTO. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Storage condition in each public health center affects the stability of the drug’s quality. During storage period, drugs should not be kept in high temperature, high humidity and direct sunlight exposure because it will induce or accelerate the drug’s quality reduction process. The result of this research suggests that public health centers in Purwokerto Timur 1 and Purwokerto Barat have the lowest drug’s quality. The samples levels sets with UV-VIS spectrophotometric method. The maximum wavelength used is 270.5 nm. Standard curves were linear in the concentration 4-12 ppm has linear equation y = 0,405 x + 0,0358, LOD of 0,814 ppm 2,716 ppm and the LOQ and RSD are 1.314%. The level respectively of each Puskesmas such as Puskesmas I of North Purwokerto 37,078 mg / tablet, and Puskesmas II of 39,059 mg / tablet, Puskesmas I of East Purwokerto 36,925 mg / tablet, Puskesmas II of East Purwokerto 40,917 mg / tablet, South Purwokerto 43,518 mg / tablet. and for West Purwokerto 36,559 mg/tablet.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Wiranti Sri Rahayu, M.Si., Apt. dan Dr. Asmiyenti Djaliasrin Djalil
Uncontrolled Keywords: Storage condition effect, quality, public health center, physic stability, furosemide tablet
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Nur Hardiansyah
Date Deposited: 29 Nov 2017 00:19
Last Modified: 29 Nov 2017 00:19
URI: http://repository.ump.ac.id/id/eprint/5733

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