Cervical cancer is a disease with the highest incidence in Indonesia. In Central Java, data on cervical cancer cases showed a fairly high rate from year to year. Cervical cancer risk factors are generally associated with low socioeconomic levels, sexual activity, contraceptive use, and hygiene. This study aims to determine correlation between hormonal contraception use, obesity, and the use of vaginal cleanser soap with the incidence of cervical cancer in Prof. Dr. Margono Soekarjo Regional Public Hospital. The type of this research was analytic observational research with case control design using retrospective approach. The sample of this research was 130 respondent, which is outpatient at Obstetric-Gynecology Department of Prof. Dr. Margono Soekarjo Regional Public Hospital. Accidental sampling was used as sampling technique. Data were analyzed by Spearman test and logistic regression. The results of statistical tests showed there was a correlation between hormonal contraceptive use (p value = 0.000) and obesity (p value = 0,033) with the incidence of cervical cancer in Prof. Dr. Margono Soekarjo Regional Public Hospital, there were no correlation between the use of vaginal cleansing soap (p value = 0,289) with the incidence of cervical cancer in Prof. Dr. Margono Soekarjo Regional Public Hospital. Hormonal contraceptive use is the most related variable with the incidence of cervical cancer in Prof. Dr. Margono Soekarjo Regional Public Hospital (OR = 4,667).