This study aims to determine the physical and chemical quality of the water droplets growing roof cave in karst landforms. Physical and chemical quality approach that flows in the secondary zone of the karst aquifer can be considered to understand the potential and as an act prevetif in the management of groundwater resources based on aquifer. This research was conducted with survey research methods. Data were collected through the sample to represent the whole population. Samples were taken by purposive sampling technique that data is taken from one point samples representing all water droplets roof of the cave. The analysis was done descriptively based on indicators of water quality. The data collection is done by taking a representative sample of water and processing is done with laboratory tests that are tailored to PERMENKES No. 416 of 1990 on Water Quality for the consumption of drinking water and treatment comparisons. The results showed that the characteristics of the relationship of physical and chemical quality of water droplets of differences in the quality of each parameter (hardness, TDS, pH) in response time for 96 Hours unchanged hardness, TDS fell by 7.4% and the pH dropped 2.7%, and after 96 Hours precipitated and was boiling 100C hardness decreased by 24%, unchanged TDS and pH fell 1.4%. On the other hand the quality of water droplets on the roof are permissible limit for drinking water consumption.