PENGARUH PENAMBAHAN KARBOKSIMETIL SELULOSA TERHADAP KARAKTERISTIK HIDROGEL FILM POLIETILENA OKSIDA UNTUK APLIKASI PEMBALUT LUKA

AINI, ANISSA NUR (2017) PENGARUH PENAMBAHAN KARBOKSIMETIL SELULOSA TERHADAP KARAKTERISTIK HIDROGEL FILM POLIETILENA OKSIDA UNTUK APLIKASI PEMBALUT LUKA. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

A research has been conducted to determine the effect of Carboxymethyl Cellulose (CMC) on the process of crosslinking and to analyze the properties of crosslinked hydrogel film for wound dressing application. The composition of Carboxymethyl Cellulose (CMC) concentration was 0% to 20% (by weight) and irradiated with electron beam. The measured characteristics included gel fraction, water vapor transmission rate and mechanical properties. The chemical and morphology structur were analyzed using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscope (SEM). The research result showed that the hydrogel crosslinking value increased with the addition of CMC as indicated by gel fraction value of PEO-CMC hydrogel which increased significantly at 5% concentration and tended to be stable at concentrations of 10%, 15% and 20%. The swelling ratio value increased at concentrations of 10%, 15% and 20% with an optimum value of 714% at 15% CMC content. The water vapor transmission rate value tended to be stable at concentration of 5-20% between 30-40 g/m2hour. Tensile strength and elongation of hydrogels increased with the addition of CMC and reached the optimal value at 10% concentration of 8,67 N/mm2 and 7,06%. The result showed that the addition of CMC can improve the characteristic of hydrogel and expected to be used for wound dressing applications.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Haryanto, S.T., M.T., Ph.D
Uncontrolled Keywords: CMC, electron beam, hydrogel, wound dressing, mechanical properties
Subjects: T Technology > TP Chemical technology
Divisions: Fakultas Teknik > Teknik Kimia S1
Depositing User: Iin Hayuningtyas
Date Deposited: 15 Jan 2018 00:20
Last Modified: 20 May 2024 03:14
URI: https://repository.ump.ac.id:80/id/eprint/6978

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