FORMULASI SHAMPO ANTIKETOMBE EKSTRAK TEH HITAM DAN TEH HIJAU SERTA UJI AKTIVITASNYA TERHADAP Pityrosporum ovale

YUNIATI, SRI (2013) FORMULASI SHAMPO ANTIKETOMBE EKSTRAK TEH HITAM DAN TEH HIJAU SERTA UJI AKTIVITASNYA TERHADAP Pityrosporum ovale. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Background : Dandruff is a minor symptom but if left treatment can causes dermatitis seborrhoic of the scalp. Appropiate selection of chemistry material which have antifungal activity as selenium sulfida, zinc pirition, ketokonazol are just control amount of dandruff and adverse effects. The green tea contain polifenol such as catechins were shown to inhibit the growth of P. ovale. Catechins in black tea fewer in number compared with green tea because it is oxidized to theaflavins and thearubigin. Objective : The research purpose was to comparing antifungal activity of shampo and extract from green tea and black tea, to deciding concentration of extract which have effective activity, and to examining phyisical characteristic of shampo. Research Methods : Method of this study is to test the activity of tea shampoos and extracts of black and green tea in various concentrations on the growth of the fungus P. ovale, testing the physical properties of shampoo that includes organoleptic, measurement of pH, viscosity and stability of the foam. Results : The physical characteristic of shampo such as organoleptis, pH, viscosity and foam stability. Fourth week observtation organoleptis and pH not changing indicate. The vicsosity of shampo reduce but not significancy. The stability foam is reduce up to minute seventh. The antifungal activity of green tea have inhibition zone rate higher than black tea. The concentration of green tea extract which most effective is 10 mg/mL with the inhibition zone 11,63 mm. The concentration of shampo green tea shampo which most effective is 5 mg/mL with the inhibition zone 11,40 mm. Antifungal activity of green tea is better than black tea because of the catechins contained intact as shown in the results of TLC. Conclusion : The physical characteristic of shampo which have observed have an stability up to fourth week. The antifungal activity of green tea is better than black tea.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Indri Hapsari, M.Si., Apt dan Binar Asrining Dhiani, M.Sc., Apt.
Uncontrolled Keywords: Pityrosporum ovale, Black tea, Green tea, Katekin, Shampo
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Dan Kh
Date Deposited: 23 Dec 2017 07:41
Last Modified: 23 Dec 2017 07:41
URI: https://repository.ump.ac.id:80/id/eprint/6408

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