AFRIDANI, RORO ROSALINA (2017) POTENSI KRIM ANTIJERAWAT MINYAK JINTAN HITAM (Nigella sativa L) PADA KULIT KELINCI LOKAL YANG DIINDUKSI Propionibacterium acnes. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

This study aims to determine the potential of anti acne of the Black cumin
oil cream (Nigella sativa L) againts P. acnes. Black cumin oil has antibacterial
acivity. It is known that black cumin oil contains a compound thymoquinone
efficacious as antibacterial. Black cumin oil is formulated in the form of a cream
and antibacterial activity againts P. acnes using Clindamisin gel for comparison.
Creams were formulated with the same base composition but different black
cumin oil concentration (5%, 10%, and 15%). In vivo assay were carried out on
rabbit skin induced by intradermal injection of P. acnes. In vivo test result for 15
days showed that black cumin oil cream had potential anti-acne activity againts
P.acnes shown from total AUC (Area Under Curve) values between acne lesions
with observation time.

Dosen Pembimbing: unspecified | unspecified
Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Dr. Nunuk Aries Nurulita, M.Si.,Apt dan Erza Genatrika, M.Sc., Apt
Uncontrolled Keywords: acne, black cumin oil, cream, in vivo
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Dan Kh
Date Deposited: 06 Oct 2017 02:32
Last Modified: 15 May 2024 01:40
URI: http://repository.ump.ac.id/id/eprint/4583

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