LAKSARI, VISDA NILA HAPPY (2017) UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL KULIT BUAH PISANG AMBON (Musa paradisiaca var.sapientum (L.) Kunt) PADA TIKUS PUTIH DENGAN INDUKSI GLUKOSA. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Diabetes mellitus is a metabolic disorder disease characterized by
increased blood glucose levels due to impaired insulin secretion or increased
insulin resistance. This study aims to determine the activity of banana ambon
banana ethanol extract (Musa paradisiaca var.sapientum (L.) Kunt.) In lowering
blood glucose levels in male white rats induced by glucose. Rats were divided into
five treatment groups, namely negative control group (NaCMC 0.5%), positive
control group (Glibenklamid), ethanol extract group of doses of 250, 375 and 500
mg / kgBB ambon bananas. Blood was taken from the vein of the tail at minute 0,
30, 60, 90, and 120, calculated from the time of glucose administration. Based on
the average blood glucose levels obtained, it can be calculated the value of AUC0-
120. AUC0-120 data were analyzed by One Way ANOVA statistical test and
continued with LSD test. From the results of the LSD analysis, there was a
significant difference (p <0.05). The banana extract ethanol extract of 500 mg /
kgBB banana doses had the highest percentage of decreased blood glucose
(42.62%), followed by a dose of 250 mg / KgBB (24.12%) and 375 mg / kgBW
(37.26). This indicates that decreasing dosage of banana extract ethanol extract
can increase antidiabetic.

Dosen Pembimbing: unspecified | unspecified
Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Dr. Tjiptasurasa, Su., Apt., dan Erza Genatrika, M.Sc., Apt.
Uncontrolled Keywords: Bananas extract ethanol extract, blood glucose level, percentage of blood glucose level
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Iin Hayuningtyas
Date Deposited: 16 Sep 2017 04:05
Last Modified: 01 Nov 2024 03:31
URI: http://repository.ump.ac.id/id/eprint/4164

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