Na-CMC as a Gelling Agent can produce toothpaste with varying consistency. Siwak wood (
Salvadora persica
) and red betel leaf (
Piper crocatum
) are often
used as active substances in toothpastes used as antibacterials in teeth. This study
aims to deter
mine the optimal concentration of Na
-
CMC as a gelling agent on
toothpaste preparations of siwak wood extract and red betel leaf extract. The
method in this research is an experimental research to determine optimal formula
toward physical characteristics of
toothpaste preparation of siwak wood extract
and red betel leaf extract by adding various Na
-
CMC concentration for stability.
Based on the results of this study, Na
-
CMC which serves as a gelling agent on
Siwak wood extract toothpaste and optimal red betel
leaf extract at a
concentration of 1.5%. The result of antibacterial test of Streptococcus mutans to
Siwak wood extract toothpaste and red betel leaf extract with 0,5%, 1%, 1,5%,
and 2% Na
-
CMC concentration resulted in inhibit zone 23,186 mm, 23,27 mm,
23
,191 mm and 23,517 mm, indicating that the variation of Na
-
CMC
concentration in toothpaste extract of siwak wood (
Salvadora persica
) and red
betel leaf extract (
Piper crocatum
) had no effect on antibacterial activity in
Streptococcus mutans bacteria