The aim of this research was to find out the effectiveness substitute, check, ask, need and revise (SCANR) strategy in teaching vocabulary (an experimental study at VIII grade students of Mts muhammadiyah 7 Kejobong in academic year 2014/2015). This research used quasi experimental research. The subjects of this research VIII A as experimental group which consisted of 32 students and VIII B as control group which consisted of 32 students. The instrument of collecting data was test. The test was done before and after the treatment, they were pre-test and post-test. The type of the test was multiple choices which consisted of 30 items both in pre-test and post-test. T-test formula was used to analyze the data. Based on the computation, t-test result was 2.830 and t-table was 1.669 at the level of significants 0.05 with the degree of freedom 62. It showed that t-test result was higher than t-table (2.830 > 1.669). Based on the research result, it can be concluded that the SCANR strategy was affective in teaching vocabulary