PENGARUH KONSENTRASI EKSTRAK ETANOL UMBI SARANG SEMUT (Myrmecodia beccarii Hook.f.) TERHADAP SIFAT FISIK SEDIAAN EMULGEL SERTA UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA

PRATIWI, SETYA (2021) PENGARUH KONSENTRASI EKSTRAK ETANOL UMBI SARANG SEMUT (Myrmecodia beccarii Hook.f.) TERHADAP SIFAT FISIK SEDIAAN EMULGEL SERTA UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA. S1 thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Background: Ants nest tuber (Myrmecodia beccarii Hook.f.) is a local plant from Merauke Regency, Papua Province which has potential as an antioxidant. The purpose of this study was to determine the effect of variations in the concentration of ethanol extract of ant nest tubers on the physical properties, antioxidant activity and sunscreen formulated in the emulgel preparation. Methods: Emulgel preparations were made in 3 formulas with varying concentrations of ethanol extract of ant nest tubers, namely FI (0.5% ethanol extract of ant nest tubers), FII (1% ethanol extract of ant nest tubers), FIII (2% ethanol extract of ant nest tubers). ant). Tests were carried out on each formula including tests of physical properties (organoleptic, pH, homogeneity, viscosity, spreadability, adhesion), stability bymethod cycling test, antioxidant activity by DPPH method, and effectiveness of sunscreen based on SPF, %Te and %Tp values. using UV-Vis spectrophotometry. Result: The physical properties of the emulgel in each formula showed good physical properties. During the cycling test, each formula showed a decrease in viscosity and pH, then analyzed using the one-way ANOVA statistical test p>0.05 where there was no significant difference in each stability test. Emulgel preparations have strong antioxidant activity, where the ICvalue50 in each formula FI=91,274 ppm; FII=76,980 ppm; FII=62.798 ppm. Minimum effectiveness of sunscreen with SPF value in each formula FI=2.38; FII=2.57; and FIII = 2.78. The %Te value in each formula is included in the extra protection category, and the %Tp value in each formula is included in thecategory sunblock. Conclusion: the addition of variations in the concentration of ethanol extract of ant nest tubers in the emulgel preparation affected the physical properties, antioxidant activity, and sunscreen.

Item Type: Thesis (S1)
Uncontrolled Keywords: ant nest tubers, emulgel, physical properties, antioxidant, sunscreen
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi S1
Depositing User: Iin Hayuningtyas
Date Deposited: 23 Nov 2022 05:51
Last Modified: 23 Nov 2022 05:51
URI: https://repository.ump.ac.id:80/id/eprint/14990

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