The study aims to determine liquidity ratio, good corporate governance, inflation, and BI interest rate towards financial distress in the manufacturing company listed in Indonesian Stock Exchange during 2014-2017 period. The population used in this study is the manufacturing company listed in the Indonesian Stock Exchange. The method of sampling this study using purposive sampling, where the selection of company samples is based on certain criteria, so obtained 49 manufacturing companies listed on the Indonesian Stock Exchange. The analysis technique used in this study is multiple linear regression analysis. The result showed that liquidity ratio and independent commissioners have effect toward financial distress, while institution ownership, inflation and BI interest rate have not affect toward financial distress.