UJI SIFAT FISIS GEL ANTIACNE EKSTRAK DAUN GAMBIR (Uncaria gambir Roxb) DALAM BASIS KARBOPOL DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus

PRASETYA, RIZKI YUDA (2011) UJI SIFAT FISIS GEL ANTIACNE EKSTRAK DAUN GAMBIR (Uncaria gambir Roxb) DALAM BASIS KARBOPOL DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Acne is an inflammatory disease of sebaceous glands are common and usually caused by bacteria such as Staphylococcus aureus. From previous studies gambier product extracts have antibacterial properties against Staphylococcus aureus. The aim of this research is to know the influence of carbopol concentration to physical characteristic and antibacterial activity of gel gambier extract against Staphylococcus auereus. Three formulas of gel were made by various carbopol concentration (1%, 1,5%, and 2%). Produced gels were tested physical characteristic (organoleptic, pH test, viscosity, homogenity, spread ability, adhesive ability, and identification of gambier extract). Antibacterial activity test was done by solid diffusion method. Viscosity data was analyzed using two way ANOVA, spread ability, adhesive ability, and antibacterial activity of gel gambier extract was analyzed using one way ANOVA with 95% of confidence level and continued by LSD (Least Significant Difference) on the data which had difference signifficancy. The result showed that the carbopol concentration increases by 1%; 1,5%; and 2% giving impairment ph and spread ability but increases adhesion and viscosity. Carbopol concentration increases by 1%; 1,5%; and 2% giving impairment antibacterial ability.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Ika Yuni Astuti, S.Si., M.Si., Apt dan Suparman, S.F., M.Sc., Apt
Uncontrolled Keywords: daya antibakteri; gel; gambir (Uncaria gambir Roxb); karbopol; Staphylococcus aureus; antibacterial activity; gel; gambier (Uncaria gambir Roxb); carbopol; Staphylococcus auereus;
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Riski Wismana
Date Deposited: 04 Jan 2018 02:45
Last Modified: 04 Jan 2018 02:45
URI: http://repository.ump.ac.id/id/eprint/6752

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