UJI TOKSISITAS SUBKRONIK PRODUK HERBAL X SECARA IN VIVO

RULLY, MENIK MUSTIKA (2016) UJI TOKSISITAS SUBKRONIK PRODUK HERBAL X SECARA IN VIVO. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Medicinal herbs “x” has been much used in society as an alternative to treat diseases, there is no scientific study of medicinal herbs the toxicity. To meet the requirements in health service system the medicine traditional formal must meet the requirements quality, safe, and efficacious. Research aims to understand symptoms toxic arising after of medicine giving herbs and hematology and picture histopathology covering the heart the kidneys, gastric, and intestines. The kind of research this using analysis experimental where researchers analyzed toxicity acute of the herbs “x” to a draft random complete, where animals test who at random and have equal opportunities to given treatment. The introduction done to determine doses used to test main. Doses used in sighting study namely 8.1 ml/kg BB and 16,3 ml/kg BB, in the probe not found death in animals test so doses used 16,3 ml/kg BB in the main study. Animals test divided into 2 groups each consisting of 5 the tail of a mouse, namely the control group given aquades and the treatment group dberi doses 16,3 ml/kg BB. The analysis independent t test and dependent t tests showed that the herbs “x” not affect, weight, the hematology ( erythrocytes and leukocytes ), and heavy organ between the control group and treatment. But, on the imagery of histopatologi indicated ASH, MFR, and improving kupfer cells to our hearts, degeneration hidropik in the kidney, oedema on the gastric, and happened enteritis and autolysis intestines. But it is not because the product herbs “x”.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Dr. Cipta Surasa,SU.,Apt. dan Dr. Nunuk Aries Nurulita S.SI.,M.Si.,Apt.
Uncontrolled Keywords: acute toxicity, product herbs, histopathology
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Nur Hardiansyah
Date Deposited: 26 Dec 2017 04:25
Last Modified: 26 Dec 2017 04:25
URI: http://repository.ump.ac.id/id/eprint/6441

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