FORMULASI SEDIAAN KRIM ANTIJERAWAT EKSTRAK DAUN SALAM (Syzygium polyanthum) DAN AKTIVITAS ANTIBAKTERINYA TERHADAP Staphylococcus aureus

KURNIAWATI, RAGIL (2015) FORMULASI SEDIAAN KRIM ANTIJERAWAT EKSTRAK DAUN SALAM (Syzygium polyanthum) DAN AKTIVITAS ANTIBAKTERINYA TERHADAP Staphylococcus aureus. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Bacground : Acne often occurs in the mid-teens and influenced by various factors, including genetics, race, season, psychological, hormonal, bacterial infections and sebaceous gland activity. Acne treatment usually use antibiotics to inhibit inflammation and kill bacteria, while the long-term use of antibiotics can lead to resistance in addition also can cause organ damage and immuno hypersensitivity. Therefore sought an alternative in treating acne by using ingredients from nature. among the plants that can be used as an acne medication is to be developed in a bay leaves topical preparations that can facilitate its use in form of a cream preparation. Objective : The research aims to make antiacne topical cream formulation containing extracts of bay leaves which are physically stable, and to know the antibacterial activity against Staphylococcus aureus Method : The research were an experimental study to examine the bay leaves extract with variations of concentration on the growth of Staphylococcus aureus in cream and then compare the antibacterial activity based on variations of concentration. All treatment conditions were created equally, to determine the antibacterial activity. Result : Bay leaves extract can be formulated in cream that physically stable and observed by the organoleptic test, pH dan viscosity. In vitro antibacterial activity of cream bay leaves extract can inhibit the growth of bacteria, proved by the clear zone in the area around the disc, but no cream formula has activity as well as a positive control. Conclusion : Bay leaves extract can be formulated in cream that physically stable, and preparations cream containing bay leaves extract can inhibit the growth of Staphylococcus aureus.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing : Indri Hapsari S.F,M.Si.,Apt dan Dr. Tjiptasurasa S.U., Apt.
Uncontrolled Keywords: polyanthum, bay leaf, cream, antibacterial, Staphylococcus aureus
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Danarto Kh
Date Deposited: 04 Feb 2017 08:04
Last Modified: 04 Feb 2017 08:04
URI: http://repository.ump.ac.id/id/eprint/625

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