EFEK HEPATOTOKSIK PADA PENGOBATAN TUBERKULOSIS DI BALAI KESEHATAN PARU MASYARAKAT PURWOKERTO

RAHAYU, RESTI WIDI (2013) EFEK HEPATOTOKSIK PADA PENGOBATAN TUBERKULOSIS DI BALAI KESEHATAN PARU MASYARAKAT PURWOKERTO. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Background : Tuberculosis has become a global health problem for the world community and it’s meaning the necessary handling of accurate and comprehensive to provide the right services at the patient's. In the application of anti-tuberculosis medicines often found side effects medication (ESO), which can cause Hepatotoxicit. Object : This study was aimed to examine whether the effect hepatotoksik raised in patients with TB who consume medicines anti-tuberculosis after treatment for 2 months. Methods : The material used in this study were the medical records of patients of tuberculosis at Balai Kesehatan Paru Masyarakat Purwokerto number of 80 patients consisting of 40 case patients and 40 control patients. Type of observational study using survey methods with cross sectional analytic, that variables which include the risk factors and variables which include the effects observed at the same time at the same time using the independent t test. Result : Hepatotoxic effects in tuberculosis patients is measured by increased AST of 8.97 (p <0.05), whereas the lower ALT increase in the amount of 10.00 (p <0.05). This means that the treatment of tuberculosis can enhance AST and ALT levels in patients. However, elevated levels of AST and ALT are still below the tolerance limit of 40 U / L so that the treatment of tuberculosis in at Balai Kesehatan Paru Masyarakat Purwokerto is not proven to cause hepatotoxic.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Didik Setiawan, M.Sc, Apt dan Drs.sudarso, Apt
Uncontrolled Keywords: tuberculosis, AST, ALT, Hepatotoxic
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Danarto Kh
Date Deposited: 25 Nov 2017 06:30
Last Modified: 25 Nov 2017 06:30
URI: http://repository.ump.ac.id/id/eprint/5675

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