SKRINING AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI HERBA PURWOCENG (Pimpinella alpina Molk)

KUSUMAWARDANI, RIZKA SARI (2014) SKRINING AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI HERBA PURWOCENG (Pimpinella alpina Molk). Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Introduction: Purwoceng is the plant was indigenous of Indonesia that grew endemically at Dieng Plateau in Central Java. Some scientific research on the efficacy and empirical use of purwoceng, however scientifically proven effects adrogenik. Object: This study aims to finding out the antibacterial activity of purwoceng to staphylococcus aureus, Echerichia coli and resistant bacteria MG42. Method: Type of research is by analyse activity of antibacteri experimental using the paper disc diffusion method, and the extract concentrations of 5, 10 and 20%. Whereas the concentration of the fraction are 0.25; 0.5; 1% with ciproloksasin antibiotics as positive control and 10% DMSO as a negative control.Calipers is used to measure the clear area around of the disc sign of inhibition. Result: Ethyl acetate extract had better antibacterial activity than extract of ethanol and petroleum ether. Average diameter of inhibition zone at concentration 20% are S. aureus of 9.97 mm, E. coli of 11.0 mm and MG42 of 9.67 mm. Conclusion: Based on the research has suggested that Extracts and fractions of purwoceng (Piminella alpina Molk) have antibacterial activity to the bacteria S. aureus, E. coli, and the isolate MG42.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Retno Wahyuningrum, M.Si., Apt. dan Binar Asrining Dhiani, M.Sc., Apt.
Uncontrolled Keywords: Ekstrak purwoceng, fraksi purwoceng (Pimpinella alpina Molk), Staphylococcus aureus, Echerichia coli, isolate MG42, Extracts, fractions, purwoceng (Pimpinella alpin Molk.), Staphylococcus aureus, Echerichia coli, isolate MG42.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Riski Wismana
Date Deposited: 07 Jul 2017 02:19
Last Modified: 07 Jul 2017 02:19
URI: http://repository.ump.ac.id/id/eprint/2373

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