EVALUASI ADVERSE DRUG REACTIONS (ADRs) PADA PASIEN ASMA DI RSUD PROF. DR. MARGONO SOEKARDJO PURWOKERTO

FEBRIANTY, NIA AULIA (2015) EVALUASI ADVERSE DRUG REACTIONS (ADRs) PADA PASIEN ASMA DI RSUD PROF. DR. MARGONO SOEKARDJO PURWOKERTO. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Background: Asthma is a chronich inflammation diseases on respiratory tract. Asthma belongs to fifth dominant causes of death in the world. It is 17,4%. Long term treatment for asthma can cause adverse drug reactions that resulted from asthma expansion. Objective: The research was aimed at knowing the number of patients who suffered adverse drug reactions, % causality from adverse drug reactions that happened on each medicine and % preventability adverse drug reactions level that happened on each medicine in pulmonary clinic of RSUD Prof. Dr. Margono Soekardjo Purwokerto. Method: The research was descriptive study using asthma patient medical record data and direct interview to the patients using algoritma naranjo scale and schumock and thornton scale in the period of March-May 2015. Results: There were 58 cases of adverse drug reactions from 33 patients in pulmonary clinic of RSUD Prof. Dr. Margono Soekardjo Purwokerto. The main causes were seretide diskus usage (fix combination fluticasone propionate and salmeterol xinafoate) of 74,14%, salbutamol usage of 15,52% and terasma expectoran syrup (fix combination terbutaline sulfate and guaifenesin) of 10,34%. Preventability level for adverse drug reactions case that happened seretide diskus usage, the highest percentage was a reactions that “not preventable” of 53,48%. Preventability level for salbutamol, the highest percentage was a reaction that “probably preventable” of 66,66% and preventability level for terasma expectoran syrup usage, the highest percentage was a reaction that “probably preventable” of 83,34%. Conclusion: A number of ADR cases in pulmonary clinic of RSUD Prof. Dr. Margono Soekardjo Purwokerto in the period of March-May 2015 were 58 ADR cases from 33 outpatients asthma patients. The antiasthma that caused ADR was seretide diskus of 74,14%.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Anjar Mahardian Kusuma, M.Sc, Apt. dan Wahyu Utaminingrum, M.Sc, Apt.
Uncontrolled Keywords: asthma, adverse drug reaction, naranjo scale, schumock and thornton scale
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Danarto Kh
Date Deposited: 08 May 2017 00:26
Last Modified: 08 May 2017 00:26
URI: http://repository.ump.ac.id/id/eprint/1835

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