AKTIVITAS ANTIDIABETES EKSTRAK ETANOL UBI JALAR UNGU (Ipomoea batatas L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ALOKSAN

SAPUTRI, KARUNIA (2015) AKTIVITAS ANTIDIABETES EKSTRAK ETANOL UBI JALAR UNGU (Ipomoea batatas L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ALOKSAN. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

DM is a metabolic disease marked by hyperglycemia. Purple sweet potato contains anthocyanin which has potential to lower blood sugar levels. This study aims to prove the hypoglycemic activity of the ethanol extract of purple sweet potato against hyperglycemic mice induced by alloxan. This is an experimental research with posttest only control group design. This study uses 20 male mice devided into 5 groups. Group I as a negative control (CMC-Na), group II as a positive control (glibenclamide 0,6 mg/kg), group III was given purple sweet potato ethanolic extract at dose of 150 mg/kg, group IV was treated with ethanol extract of purple sweet potato at dose of 300 mg/kg, and group V was treated with ethanolic extract of purple sweet potato at dose of 600 mg/kg. The result showed that ethanolic extract of purple sweet potato possess hypoglycemic activity. Ethanolic extract of purple sweet potato at doses of 150 mg/kgBB and 300 mg/kgBB showed the strongest activity among three used doses, which are equivalent to that of glibenclamid at dose of 0,6 mg/kgBB.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Susanti, M.Phil.,Apt dan Dwi Hartanti, M. Farm., Apt
Uncontrolled Keywords: Diabetes mellitus, hypoglycemic, ethanolic extract of sweet potato purple
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Danarto Kh
Date Deposited: 08 May 2017 00:18
Last Modified: 08 May 2017 00:18
URI: http://repository.ump.ac.id/id/eprint/1833

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