PENGARUH REKONSILIASI OBAT (MEDICATION RECONCILIATION) TERHADAP POTENSI INTERAKSI OBAT PADA PASIEN RAWAT INAP DI RSUD PROF. DR. MARGONO SOEKARJO PURWOKERTO

BINTARIZKI, LILA (2016) PENGARUH REKONSILIASI OBAT (MEDICATION RECONCILIATION) TERHADAP POTENSI INTERAKSI OBAT PADA PASIEN RAWAT INAP DI RSUD PROF. DR. MARGONO SOEKARJO PURWOKERTO. Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PURWOKERTO.

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Abstract

Background : Medication reconciliation is a pharmaceutical cares and in there is the process of comparing the obtained patient treatment instructions. Medication reconciliation plays on important role in reducing the incidence of medication errors in particular drug interactions and potentially dangerous to the patients. A study in Nepal known drug-drug interaction events by 53% in patient in internal medicine wards and ICU with and average of 8,53 of drug users by prescription medication. In the another study also showed that medication reconciliation proven to be a effective strategy to reduce the incidence of drug interactions. Therefore, the presence of medication reconciliation can reducing the incidence of drug interactions and can improving patient treatment outcomes. Research purposes : Measure the influence of medication reconciliation to the reduction of potential drug interactions in hospitalzed patient on RSUD Prof Dr. Margono Soekarjo Purwokerto. Research methods : This research was a descriptive study with prospective data collection methods through observation based on patient medication reconciliation sheets in RSUD Prof. Dr. Margono Soekarjo Purwokerto. Result : Samples used in this study were 95 patient in RSUD Prof. Dr. Margono Soekarjo Purwokerto. From 95 patient, there were 52 patient (54,73%) with the drug interaction potentials, after medication reconciliation process there been a decrease of 20 patient (21,05%) with no drug interaction potential in their treatments, while 32 patient (33,68%) still have potential drug interaction in their treatments. And based on the decision of continuing in medication reconciliation, there were 43 cases drug interaction with the severity of minor 72,10% (31 cases) and the severity of moderate 27,90% (12 cases). And 15 type of drug interactions with pharmacodynamic interaction mechanism 80% (12 type of drug combinations) and pharmacokinetic interaction mechanism 20% (3 type of drug combinations). Conclusion : The incident of drug interactions that exist are 52 patients (54,73%) after medication reconciliation processed there were decrease of 20 patients (21,05%) with no drugs interaction, while 32 patients (33,68%) still has drugs interaction. Thereforepharmaceutical cares as a medication reconciliation in RSUD Prof. Dr. Margono Soekarjo Purwokerto in not optimally, because there is still a drug interaction in patient prescriptions after process of mediaction reconciliation occurred.

Item Type: Thesis (Bachelor)
Additional Information: Pembimbing: Wahyu Utaminingrum M.Sc., Apt. dan Anjar Mahardian Kusuma M.Sc., Apt.
Uncontrolled Keywords: Phramaceutical cares, Medication reconciliation, Drug interaction
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Farmasi > Farmasi
Depositing User: Danarto Kh
Date Deposited: 06 Apr 2017 05:28
Last Modified: 06 Apr 2017 05:28
URI: http://repository.ump.ac.id/id/eprint/1346

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